Abiraterone: Dosage, Uses and Side Effects

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Abiraterone: Dosage, Uses and Side Effects

Introduction

Abiraterone is a medicine that belongs to the anti-androgen (anti-testosterone) class of medications. It acts by inhibiting testosterone synthesis, a male hormone that can stimulate the growth and spread of prostate cancer. It is used in conjunction with steroids (prednisone or methylprednisolone) to treat prostate cancer that has progressed to other regions of the body. It should not be used by women or children.



Dosage

The recommended dose of abiraterone acetate is 1,000 mg (two 500 mg tablets or four 250 mg tablets) orally once daily in conjunction with 5 mg of prednisone orally twice daily. Dosing instructions for this drug may differ between brands. Do not switch brands of this medication without first consulting your doctor. As recommended by your doctor, take this medication by mouth on an empty stomach (at least 1 hour before or 2 hours after food). Taking abiraterone with food significantly increases the quantity of this drug in your body and raises the risk of side effects. Completely swallow the tablets. The tablets should not be crushed or chewed.


Side Effects

The following are some of the most common abiraterone acetate adverse effects:

  • Low potassium levels in the blood High blood pressure
  • Infection of the urinary tract
  • Diarrhea
  • Triglyceride levels in the blood have risen.
  • Sepsis
  • Heart failure
  • Angina pectoris (chest pain)
  • Atrioventricular fibrillation
  • Tachycardia
  • Dyspepsia
  • Urine with blood
  • Edoema of the periphery
  • Fracture
The following are some significant adverse effects of abiraterone acetate:

  • Reactions to allergens
  • Liver issues
  • Adrenal issues
  • Mineral deficiency
  • Heart issues
If you notice any of these adverse effects, call your doctor right away.

Abiraterone can harm an unborn infant if a pregnant woman is exposed to it or if the father is taking it at the time of conception or during pregnancy. If your sex partner is pregnant or has the potential to get pregnant, use effective birth control. Continue to use birth control for at least three weeks following your final dose. Abiraterone pills should not be handled by pregnant or planning to become pregnant women. A shattered tablet's medication could be absorbed through the skin.


Uses

Abiraterone is a cancer treatment that is used to treat prostate cancer that has progressed to other places of the body. It is used in men who cannot be treated with surgery or other medications for prostate cancer. It reduces androgen production in the body. Androgens are male hormones that can stimulate prostate tumour growth. To reduce some of the negative effects of abiraterone, it is used with steroid medicine (prednisone or methylprednisolone). Abiraterone may potentially be used for uses other than those specified in this drug guide.

Conclusion

Finally, Abiraterone is a drug that can help limit the growth and spread of prostate cancer by inhibiting testosterone production. It is combined with steroid medication to alleviate some of the negative effects. Women and children should not use it. It has some dangerous adverse effects that necessitate medical treatment. It should be taken on an empty stomach, as instructed by the doctor. It can harm an unborn child if a pregnant woman is exposed to it or if the father takes it. It is critical to see your doctor before beginning or discontinuing this medicine.

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